منابع مشابه
Pseudocholinesterase activity and atracurium v. suxamethonium block.
Serum pseudocholinesterase activity in pregnant women was assayed spectrophotometrically using either propionylthiocholine or suxamethonium as substrate. All patients had a normal phenotype as indicated by normal dibucaine and fluoride numbers. However, the mean cholinesterase activity was lower than in the general population. There was a negative correlation between cholinesterase activity and...
متن کاملAtracurium compared with suxamethonium for outpatient laparoscopy.
I.v. atracurium 0.3 mg kg-1 and suxamethonium 1.6 mg kg-1 plus infusion were compared for use in outpatient laparoscopy. Thirty patients were randomly assigned to receive one of the two blocking drugs. Both drugs proved suitable for use in outpatient laparoscopy, but atracurium may have advantages if the operation proceeds directly to laparotomy.
متن کاملPharmacokinetics and pharmacodynamics of atracurium with and without previous suxamethonium administration.
Suxamethonium increases neuromuscular block produced by non-depolarizing agents administered subsequently. To determine if this effect has a pharmacokinetic or pharmacodynamic origin, 18 ASA physical status I or II adults received atracurium 0.2 mg kg-1, with (n = 10) or without (n = 8) previous injection of suxamethonium 1 mg kg-1, during a thiopentone-nitrous oxide-isoflurane (0.5% end-tidal)...
متن کاملAtracurium and intraocular pressure.
The effect of atracurium on intraocular pressure was studied by comparing it with pancuronium in a randomised controlled trial. The intraocular pressure was measured in patients undergoing cataract surgery before administration of the muscle relaxant, at 1, 3, and 5 minutes after its administration, and at 1 minute after tracheal intubation. Atracurium was found to decrease intraocular pressure...
متن کاملGoodbye suxamethonium!
No drugs in anaesthesia are more problematic than suxamethonium. Yet, no drugs have survived as suxamethonium does in spite of crisis after crisis, and attempt after attempt at its replacement. For decades, suxamethonium has taught us neuromuscular pharmacology and provided us with an encyclopaedia of side effects, while benefiting millions and millions of our anaesthetised patients. With the a...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1991
ISSN: 0007-0912
DOI: 10.1093/bja/67.4.502-a